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CDC releases viruses for novel H1N1 vaccine development

first_imgMay 27, 2009 (CIDRAP News) – Sanofi Pasteur announced today that it has received a novel H1N1 influenza vaccine virus from the Centers for Disease Control and Prevention (CDC), moving the company a step closer to starting production of a vaccine.CDC spokesman Tom Skinner said this afternoon that the agency is also sending the vaccine virus to other manufacturers, located overseas, who should receive the samples within a few days.Jeff McLaughlin, a spokesman for vaccine maker GlaxoSmithKline (GSK), said today he couldn’t confirm GSK’s receipt of the vaccine strain, but added, “We understand that the CDC is in the process of shipping the strain to all the relevant manufacturers.”CDC and World Health Organization (WHO) officials had predicted that the CDC would release H1N1 vaccine viruses to manufacturers by the end of May. WHO officials have said that production of H1N1 vaccines is most likely to begin in July.The preparation of a vaccine strain involves combining a clinical sample of the target virus with another influenza virus that grows in eggs. This process creates a new virus that has some of the properties of the target virus and the ability to grow in eggs, the US Department of Health and Human Services noted today in a fact sheet on vaccine development activities. Most flu vaccines are still produced by growing them in eggs.Wayne Pisano, president of Sanofi Pasteur, said in a news release, “As a company committed to protecting human health, Sanofi Pasteur looks forward to quickly understanding how this virus performs in a vaccine manufacturing environment and developing a working seed that will enable large-scale production.”Sanofi will now begin “passaging” the virus, referring to “the process for acclimating virus to grow in a production environment at optimum yield,” the company said. The process will take about 2 weeks.”Following quality controls, Sanofi Pasteur will be prepared to begin industrial production as soon as directed by public health agencies,” the statement added.Health officials have estimated it would take manufacturers 4 to 6 months from when they receive the vaccine strain to start producing a vaccine in quantity. But a Sanofi spokeswoman said last week that the company may be able to start producing its first doses in 3 to 4 months.Sanofi and GSK both announced within the past few days that they had received US government orders for novel H1N1 vaccines.In related news, the WHO has recommended that vaccines for the novel H1N1 influenza virus be based on an isolate from California, saying most H1N1 viruses isolated so far are very similar to it.A majority of the novel H1N1 viruses isolated so far are antigenically and genetically related to the isolate known as A/California/7/2009 (H1N1), the WHO said in a statement posted online yesterday.The WHO said that its collaborating laboratories, certain regulatory agency laboratories, and other partners are developing reassortant viruses antigenically similar to the California strain for use in vaccines.Skinner, of the CDC, said the agency used the California strain in making the vaccine virus now being released to manufacturers.WHO spokesman Gregory Hartl said several other WHO collaborating centers and regulatory laboratories are developing novel H1N1 vaccine viruses. He said they include St. Jude Children’s Research Hospital in Memphis, a US Food and Drug Administration lab, and facilities in Japan, the United Kingdom, and Australia.See also: May 27 Sanofi press releaseMay 26 CIDRAP News story “Companies receive HHS orders for novel flu vaccine”WHO recommendation on strain for vaccine developmentlast_img read more

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No. 3 seed Boeheim’s Army survives late scare to edge No. 11 seed GaelNation in double OT, 106-100, to advance to Super 16

first_imgPHILADELPHIA — Donte Greene waved both hands in the air. He pounded his feet and let out a roar. His and-one in double overtime finally provided a group of Syracuse fans reason to let out a collective sigh of relief, then rise to their feet in unison to celebrate a 106-100 double-overtime victory on Sunday afternoon.A few minutes earlier, when GaelNation’s D’Angelo Harrison tied the score with a long 3, capping off a 20-point second-half comeback, he waved to the very same section of orange. From around midcourt, Harrison, a two-time First Team All-Big East selection at St. John’s, stared at the contingent of fans he had just stunned. They sat, clad in orange, and hushed.This time, with Boeheim’s Army again leading after Green’s and-one, the fans could rejoice. The Syracuse Alumni, up by 15 at the break and 20 early in the second half, let GaelNation, a group of Iona alumni, erupt for a furious second-half comeback to pull within one. Then Steven Burtt scored a transition layup to give GaelNation its largest lead of the game, three, with two minutes to play.“We got a little stagnant offensively,” head coach and former SU big man Ryan Blackwell said. “We were a little bit tired. We weren’t communicating when they made a run. But we kept our composure and executed … we made individual plays.”With each basket, the celebration grew fiercer, the towel waves stronger and the jolt off of the GaelNation bench a little bit more passionate. Fans in maroon banged their feet to the bleachers as GaelNation inched closer to an upset over a team with significant Final Four experience on the floor.AdvertisementThis is placeholder textNo. 3 seed Boeheim’s Army staved off a 20-point comeback from No. 11 seed GaelNation in double overtime on Sunday at the campus of Philadelphia University. Greene finished with a team-high 28 points in his first game this year and, for the third consecutive year, Boeheim’s Army will advance to the Super 16 of The Basketball Tournament, a 64-team, single-elimination tournament that awards a $2 million grand prize. (In November, the Orange hosts Iona for the first time since 2010.)The Syracuse alumni, now boasting a 7-2 record over three summers in the tournament, will play July 20 in Brooklyn. Should No. 2 seed Supernova move on in its matchup later on Sunday, Boeheim’s Army will face former members of the Villanova Wildcats.Both Blackwell and Cooney pointed to the difference a few days may make. Last year, only four players practiced for a couple of days in Syracuse. This year, all eight players played pickup ball in the Carmelo K. Anthony Basketball Center the week leading up to this weekend’s tournament. Both said that the extra repetitions proved critical in edging out the victory Sunday, and that they will dictate how far Boeheim’s Army can go this summer.Saturday night on the same floor in Philadelphia, Boeheim’s Army scored 14 points before the No. 14 seed DuBois Dream made a basket, in a 99-66 victory in the opening round of the tournament. Brandon Triche tallied a triple-double (11 points, 11 rebounds, 12 assists) and John Gillon scored a game-high 26 points, hitting four 3-pointers and handing out five assists.Matthew Gutierrez | Asst. Sports EditorIn round two, Greene kicked off the scoring brigade with a baseline jumper. Forty-nine first-half points followed, including a handful of Greene 3-pointers, a two-handed jam by 7-footer DaShonte Riley and a nifty drive by Eric Devendorf, who scored 23. The 2009 Syracuse graduate, who ranks 14th on the program’s all-time scoring list, was trapped in the corner with nowhere to run. He nearly lost the handle, then hesitated, spun baseline and pounded two dribbles before laying in a basket.What followed in the second half hardly mirrored that of the night prior, when Syracuse trounced a team without a single former Division I player. C.J. Fair, a former First Team All-ACC selection and forward on Syracuse’s 2013 Final Four team, grooved his way to a transition dunk to create a 20-point advantage. Trevor Cooney, who two years ago started at guard on Syracuse’s Final Four team, drilled a pair of 3s.“Our zone bothered them a bit” Cooney said. “And we found a rhythm.”But then GaelNation found its stride, using its length inside to gain loose rebounds and hitting several 3-pointers against Boeheim’s Army’s 2-3 zone. Burtt, a left-handed guard, used a mix of elusiveness, craftiness and shooting prowess to score a game-high 34 points and lead the charge. Missed box outs, sometimes sloppy defense and more than 13 offensive rebounds let GaelNation sneak back in.That is until Greene allowed Boeheim’s Army to regain its footing in double overtime.“We want the $2 million,” Greene said. Comments Published on July 9, 2017 at 5:21 pm Contact Matthew: [email protected] | @MatthewGut21 Facebook Twitter Google+last_img read more

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LIVE BLOG – Truck Rally – FSJ for LNG

first_imgThis is a live blog of the Truck Rally in Fort St. John to show support for the Pacific Northwest LNG project and the liquified natural gas industry in Canada.  The rally will start with vehicles leaving from south of Fort St. John at 11:30 a.m. Wednesday March 16.  The convoy will head towards the boat launch at Charlie Lake where residents will hear speeches and enjoy a BBQ.If technology is on our side, this blog will be updated with photos and live tweets from the event.  On top of this, we hope to be able to broadcast live video from Charlie Lake and the rally starting at around 12 p.m.  Watch for the video on our Facebook page, by clicking here.LIVE BLOG – Truck Rally – FSJ for LNGLive Blog Truck Rally – FSJ for LNG – Advertisement –last_img read more

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