May 27, 2009 (CIDRAP News) – Sanofi Pasteur announced today that it has received a novel H1N1 influenza vaccine virus from the Centers for Disease Control and Prevention (CDC), moving the company a step closer to starting production of a vaccine.CDC spokesman Tom Skinner said this afternoon that the agency is also sending the vaccine virus to other manufacturers, located overseas, who should receive the samples within a few days.Jeff McLaughlin, a spokesman for vaccine maker GlaxoSmithKline (GSK), said today he couldn’t confirm GSK’s receipt of the vaccine strain, but added, “We understand that the CDC is in the process of shipping the strain to all the relevant manufacturers.”CDC and World Health Organization (WHO) officials had predicted that the CDC would release H1N1 vaccine viruses to manufacturers by the end of May. WHO officials have said that production of H1N1 vaccines is most likely to begin in July.The preparation of a vaccine strain involves combining a clinical sample of the target virus with another influenza virus that grows in eggs. This process creates a new virus that has some of the properties of the target virus and the ability to grow in eggs, the US Department of Health and Human Services noted today in a fact sheet on vaccine development activities. Most flu vaccines are still produced by growing them in eggs.Wayne Pisano, president of Sanofi Pasteur, said in a news release, “As a company committed to protecting human health, Sanofi Pasteur looks forward to quickly understanding how this virus performs in a vaccine manufacturing environment and developing a working seed that will enable large-scale production.”Sanofi will now begin “passaging” the virus, referring to “the process for acclimating virus to grow in a production environment at optimum yield,” the company said. The process will take about 2 weeks.”Following quality controls, Sanofi Pasteur will be prepared to begin industrial production as soon as directed by public health agencies,” the statement added.Health officials have estimated it would take manufacturers 4 to 6 months from when they receive the vaccine strain to start producing a vaccine in quantity. But a Sanofi spokeswoman said last week that the company may be able to start producing its first doses in 3 to 4 months.Sanofi and GSK both announced within the past few days that they had received US government orders for novel H1N1 vaccines.In related news, the WHO has recommended that vaccines for the novel H1N1 influenza virus be based on an isolate from California, saying most H1N1 viruses isolated so far are very similar to it.A majority of the novel H1N1 viruses isolated so far are antigenically and genetically related to the isolate known as A/California/7/2009 (H1N1), the WHO said in a statement posted online yesterday.The WHO said that its collaborating laboratories, certain regulatory agency laboratories, and other partners are developing reassortant viruses antigenically similar to the California strain for use in vaccines.Skinner, of the CDC, said the agency used the California strain in making the vaccine virus now being released to manufacturers.WHO spokesman Gregory Hartl said several other WHO collaborating centers and regulatory laboratories are developing novel H1N1 vaccine viruses. He said they include St. Jude Children’s Research Hospital in Memphis, a US Food and Drug Administration lab, and facilities in Japan, the United Kingdom, and Australia.See also: May 27 Sanofi press releaseMay 26 CIDRAP News story “Companies receive HHS orders for novel flu vaccine”WHO recommendation on strain for vaccine development
“I gave the task force three tasks, namely detecting firms planning to relocate, analyzing the ease [of doing business] offered by other countries and, importantly, making a decision in a negotiation,” Bahlil stated in a press release on June 19.The establishment of the task force was part of the government’s efforts to minimize the economic impact of COVID-19 on foreign direct investment, which fell 9.2 percent year-on-year (yoy) to Rp 98 trillion (US$6.9 billion) in the first quarter of 2020.The coronavirus outbreak, which was first detected in China, has strained Indonesia’s foreign direct investment as projects have been delayed as a result of social restrictions to contain the spread of the virus. The pandemic has also disrupted global supply chains and has made some companies question their heavy reliance on China.Bahlil, who formerly led the Association of Young Indonesian Entrepreneurs (HIPMI), declined to provide details of the businesses planning to relocate to the country, saying that he was “waiting for the President himself to announce them”.BKPM data shows that Japanese firms invested $604 million in the first three months of this year, making it the fourth-largest country of origin for foreign direct investment in the period. South Korean firms were the eighth largest, investing $130.4 million, followed by the United States with $114.1 million.Topics : The government has established a special task force to attract businesses leaving China and facilitate their relocation to Indonesia.American, Japanese and South Korean companies are reportedly in discussions with the Investment Coordinating Board (BKPM) over their potential relocation to the Batang and Brebes industrial districts in Central Java, which are currently under development.According to BKPM head Bahlil Lahadalia, the agency has completed 60 percent of the relocation process for some firms.
Close Forgot password? Please put in your email: Send me my password! Close message Login This blog post All blog posts Subscribe to this blog post’s comments through… RSS Feed Subscribe via email Subscribe Subscribe to this blog’s comments through… RSS Feed Subscribe via email Subscribe Follow the discussion Comments Logging you in… Close Login to IntenseDebate Or create an account Username or Email: Password: Forgot login? Cancel Login Close WordPress.com Username or Email: Password: Lost your password? Cancel Login Dashboard | Edit profile | Logout Logged in as Admin Options Disable comments for this page Save Settings You are about to flag this comment as being inappropriate. Please explain why you are flagging this comment in the text box below and submit your report. The blog admin will be notified. Thank you for your input. There are no comments posted yet. Be the first one! Post a new comment Enter text right here! Comment as a Guest, or login: Login to IntenseDebate Login to WordPress.com Login to Twitter Go back Tweet this comment Connected as (Logout) Email (optional) Not displayed publicly. Name Email Website (optional) Displayed next to your comments. Not displayed publicly. If you have a website, link to it here. Posting anonymously. Tweet this comment Submit Comment Subscribe to None Replies All new comments Comments by IntenseDebate Enter text right here! Reply as a Guest, or login: Login to IntenseDebate Login to WordPress.com Login to Twitter Go back Tweet this comment Connected as (Logout) Email (optional) Not displayed publicly. Name Email Website (optional) Displayed next to your comments. Not displayed publicly. If you have a website, link to it here. Posting anonymously. Tweet this comment Cancel Submit Comment Subscribe to None Replies All new comments Curtiss Metzby Tracy McCue, Sumner Newscow â€” The Dore will be holding its third annual Fast Pitch Softball Tournament which will include a raffle and auction with all proceeds going to the Curtiss Metz Fund.Metz, 27, of Wellington was recently treated for Endocarditis, an inflammation of the inside lining of the heart chambers and heart valves. He underwent an aerobic valve replacement. As a result, the Metz family incurred a huge debt because he was uninsured at the time of the operations.The tournament and raffle will begin July 29 and run through Aug. 3 where a drawing will be held on Aug. 3 in Mayfield.Raffle tickets can be purchased at the Security State Bank, The Dore and at Countryside Motors. Raffle prices are one for $20, three for $50 or 10 for $100. An auction will be held on Aug. 3 and include a Biz sign, neon, crown bag quilt and more.Â Game times for the tournament will be weekdays 6 and 8 p.m., weekends 5, 6:30 and 8 p.m.There will be a Home Run Derby qualifier nightly.For more information contact Kip Etter at 440-7379.Follow us on Twitter.